Immune System and Hepatocellular Carcinoma (HCC): New Insights into HCC Progression

نویسندگان

چکیده

According to the WHO’s recently released worldwide cancer data for 2020, liver ranks sixth in morbidity and third mortality among all malignancies. Hepatocellular carcinoma (HCC), most common kind of cancer, accounts approximately 80% primary malignancies is one leading causes death globally. The intractable tumor microenvironment plays an important role development progression HCC three major unresolved issues clinical practice (cancer recurrence, fatal metastasis, refractory microenvironment). Despite significant advances, improved molecular cellular characterization still required since it genesis HCC. purpose this review present overview immune microenvironment, distinct constituents, current therapies, potential immunotherapy methods.

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ژورنال

عنوان ژورنال: International Journal of Molecular Sciences

سال: 2023

ISSN: ['1661-6596', '1422-0067']

DOI: https://doi.org/10.3390/ijms241411471